Infertility Treatment
In the treatment of infertility in the past few years has been tremendous progress, and this was primarily due to a number of outstanding achievements in the field of assisted reproduction technologies. These techniques combine the use of drugs for infertility treatment (hormone therapy) with artificial insemination, which uses any of the following techniques: intrauterine insemination, in vitro fertilization, introduction of gametes into the fallopian tubes, the introduction of the zygote into the fallopian tubes or donor oocyst (egg).
Medicine against infertility
Medicines against infertility are intended to stimulate the ovaries to produce eggs during one cycle of stimulation of your own hormones to ensure that they perform their duties more effectively, or complete replacement of their “outside” hormones.
Clomifen, produced under the brand names Clomid or serofen and used for the treatment of infertility problems for over twenty five years, is a drug which increases your body’s own production of essential hormones. Taken in pill form, clomifen causes the pituitary gland to produce more hormone that stimulates the formation of folliculin. Follicle-stimulating hormone in turn stimulates ovulation and sometimes so well fulfills its mission, it leads to the maturation of two or more eggs, which gives women taking this drug, ten percent chance of the birth of twins.
Side effects
Time and painless, side effects clomid can cause anxiety or even anxiety, if you do not know about them. These include the following phenomena:
1. The flow of blood, similar to those you can experience during menopause due to increased levels of follicle stimulating hormone formation.
2. Poor visual disturbances, manifested mainly in the dark, when the colors will blend, or when you turn the heads of the subjects appear shadows.
3. Mood swings, irritability, transitions from the expression of cardiac emotions, inability to concentrate and feeling of lack of space. In fact, may appear the same symptoms as in the most severe cases of premenstrual syndrome.
4. Excessive sensitivity and pain in the ovaries, possibly due to the fact that the ovaries are stretched, when used simultaneously as many oocytes.
5. Cysts on the ovaries, but not those cysts that require surgical intervention, but simple, fluid-filled follicles, which are not opened to release the egg during ovulation, and continue to grow. Almost always they are completely harmless and disappear after the next menstrual period, but in rare cases require treatment.
Pergonal and hysterodynia – is reinforced by the shape of human formon stimulating the formation of folliculin. They divorced in distilled water and introduced into the form of daily intramuscular injections. Unlike clomid these drugs, bypassing the pituitary acts directly on the ovaries. They usually cause simultaneous release of multiple eggs, thereby increasing the possibility of conception. Their other advantage over the natural hormone is that they can control the exact time of ovulation, making it possible to further carry out such additional activities such as intrauterine insemination, in vitro fertilization, or transplantation of gametes in the fallopian tube.
In the conduct of stimulation required constant medical supervision, to ensure that your ovaries are stimulated not too weak, but not too much. Examination by intrauterine ultrasound can count the number of eggs and to assess their maturity, while the blood test to determine the level of estrogen has shown the degree of ovarian stimulation and egg ready to be released in the fallopian tubes.
When the eggs mature, with an intramuscular injection of human chorion gonadotropin, a hormone normally produced in large quantities in the beginning of pregnancy, approximately thirty-six hours delayed the beginning of ovulation. This interval gives time to plan the sexual intercourse, insemination or search for eggs in vitro fertilization or the introduction of gametes into the fallopian tube. This hormone is sometimes used together with clomid to leave time for sexual intercourse or artificial insemination.
Due to the large number of eggs, usually produced by the ovaries at the use of first-estrus or hysterodynia, a woman who became pregnant with their help, has a 20% chance of conceiving twins, 5% of conceiving triplets and 1% fertilization of four eggs at a time. But the formation of more than three embryos increases risk of miscarriage or birth of severely premature babies, so in these cases is usually recommended correction of pregnancy – delete superfluous embryos.
Side effects
Treatment with pergonala or hysterodynia usually leads to poor bloating and delay in the body of water during the week following the ovulation. These symptoms are usually transient and do not give a recurrence. However, excessive ovarian stimulation may develop nausea, a sharp increase in stomach, severe weight gain and edema of the ovary – a situation requiring immediate assistance, medical, or possibly even hospitalization for careful regulation of water-salt balance. The probability of such complications less than 1%.
